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Order Code VLTU Volatile Screen, Random, Urine

Reporting Name

Volatile Scrn, U

Useful For

Detecting the presence of acetone, methanol, isopropanol, or ethanol in urine with subsequent quantitation

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Urine


Ordering Guidance


For best clinical correlation, the recommended tests are either VLTS / Volatile Screen, Serum; or VLTB / Volatile Screen, Blood.



Specimen Required


Supplies: Urine Tubes, 10 mL (T068)

Container/Tube: Plastic, 10-mL urine tube

Specimen Volume: 10 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative is required.


Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Refrigerated (preferred) 14 days
  Frozen  28 days
  Ambient  24 hours

Reference Values

Methanol:

Not detected (Positive results are quantitated.)

Cutoff concentration: 10 mg/dL

Toxic concentration: ≥10 mg/dL

 

Ethanol:

Not detected (Positive results are quantitated.)

Cutoff concentration: 10 mg/dL

 

Isopropanol:

Not detected (Positive results are quantitated.)

Cutoff concentration: 10 mg/dL

Toxic concentration: ≥10 mg/dL

 

Acetone:

Not detected (Positive results are quantitated.)

Cutoff concentration: 10 mg/dL

Toxic concentration: ≥10 mg/dL

Day(s) Performed

Monday through Saturday

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

G0480

80320 (if appropriate for select payers)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
VLTU Volatile Scrn, U 24350-1

 

Result ID Test Result Name Result LOINC Value
8826 Volatile Scrn, U 12983-3
30904 Methanol, U 5695-2
30905 Ethanol, U 5645-7
30906 Acetone, U 5570-7
30907 Isopropanol, U 9434-2
34378 Chain of Custody 77202-0

Clinical Information

Urine provides a medium for easy screening for methanol, ethanol, isopropanol, and acetone.

Clinical Reference

1. Langman LJ, Bechtel LK, Holstege CP. Clinical toxicology. In: Rifai N, Chiu RWK, Young I, Burnham CD, Wittwer CT, eds. Tietz Textbook of Laboratory Medicine. 7th ed. Elsevier; 2023:chap 43

2. Mayfield J, Mihic SJ. Ethanol. In: Brunton LL, Knollmann BC. Goodman and Gilman's: The Pharmacological Basis of Therapeutics. 13th ed. McGraw-Hill Education; 2022:chap 27

3. Olson KR, Anderson IB, Benowitz NL, et al. Specific Poisons and Drugs: Diagnosis and Treatment. In: Poisoning and Drug Overdose. 8th ed. McGraw-Hill; 2022:section II

Report Available

1 to 2 days

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Method Name

Headspace Gas Chromatography with Flame Ionization Detector (HSGC-FID)

Secondary ID

8826

Testing Algorithm

This test includes analysis of methanol, ethanol, isopropanol, and acetone.

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.